Office O03.001
florian.leisinger@clutterunibas.ch
phone +41 (0)61 207 59 40
University Basel
Department of chemistry
Mattenstrasse 24a, BPR 1096
4058 Basel
Publications
Wen, X.; Leisinger, F.; Leopold, V.; Seebeck, F. P.
"Synthetic reagents for enzyme-catalyzed methylation"
Angew. Chem. Int. Ed. 2022, e202208746.
Beliaeva M. A.; Leisinger F.; Seebeck, F. P.
"In-Vitro Reconstitution of a Five-Step Pathway for Bacterial Ergothioneine Catabolism."
ACS Chem. Biol., 2021, in press.
Leisinger F.; Miarzlou, D.A.; Seebeck, F. P.
"Non-coordinative binding of O2 at the active site center of a copper-dependent enzyme."
Angew. Chem. Int. Ed., 2021, in press.
Miarzlou, D.A.; Leisinger, F.; Joss, D.; Häussinger, D.; Seebeck, F. P.
"Structure of formylglycin-generating enzyme in complex with copper and a substrate reveals an acidic pocket for binding and activation of molecular oxygen."
Chem.Sci., 2019, 10, 7049 - 7058.
Maurer, A*; Leisinger, F.*; Lim, D.; Seebeck, F. P.
"Structure and mechanism of ergothionase from Treponema denticola."
Chem. Eur. J., 2019, 25, 10298 - 10303.
Leisinger, F.; Burn R.; Meury, M.; Lukat, P.; Seebeck, F. P.
Structural and mechanistic basis for anaerobic ergothioneine biosynthesis.
J. Am. Chem. Soc., 2019, 141, 6906 - 6914.