FS

42.

Schneider P.; Henssen B.; Paschold B.; Chapple B.P.; Schatton M.; Seebeck, F. P.; Classen T.; Pietruszka J. 
"Biocatalytic C3-Indole Methylation – A Useful Tool for the Natural Product Inspired Stereoselective Synthesis of Pyrroloindoles."
Angew. Chem. Int. Ed.2021in press.


MB

41.

Beliaeva M. A.; Leisinger F.; Seebeck, F. P. 
"In Vitro Reconstitution of a Five-Step Pathway for Bacterial Ergothioneine Catabolism."
ACS Chem. Biol.2021, 16, 397 - 403.


GA

40.

Leisinger F.; Miarzlou, D.A.; Seebeck, F. P. 
"Non-coordinative binding of Oat the active site center of a copper-dependent enzyme."
Angew. Chem. Int. Ed.2021, 133, 6219 - 6224.


MB

39.

Beliaeva M. A.; Burn R.; Lim D.; Seebeck, F. P.
''In vitro production of ergothioneine isotopologues''
Angew. Chem. Int. Ed. 2020, 60, 5209 - 5212.


DL

38.

Lim D.; Wen X.; Seebeck, F. P.
''Selenoimidazolium salts as supramolecular reagents for protein alkylation''
ChemBioChem. 2020, 21, 3515 - 3520.


AS

37.

Stampfli A. R.; Seebeck, F. P.
''The catalytic mechanism of sulfoxide synthases''
Current Opinion in Chemical Biology 2020, 59, 111 - 118.


SF

36.

Flückiger S.; Igareta N. V.; Seebeck, F. P.
''Convergent evolution of fungal cysteine dioxygenases''
ChemBioChem. 2020, 21, 3082 - 3086.



ASrev

34.

Stampfli A. R.; Blankenfeldt, W; Seebeck, F. P.
''Structural basis of ergothioneine biosynthesis''
Current Opinion in Structural Biology 2020, 65, 1 - 8.


LC

33.

Liao C.; Seebeck, F. P.
''Asymmetric β-methylation of L- and D-α-amino acids by a self-contained enzyme cascade''
Angew. Chem. Int. Ed. 2020, 59, 7184 - 7187.


RB

32.

Milito, A.; Castellano, I.; Burn, R.; Seebeck, F. P.; Burnet, C.; Palumbo, A.
''First evidence of ovothiol biosynthesis in marine diatoms''
Free Radic Biol Med. 2020, 152, 680 - 688.


GK

31.

Goncharenko, K.V.; Flückiger S.; Liao C.; Lim, D.; Stampfli A.R.; Seebeck, F. P.
''Selenocysteine as a substrate, an inhibitor and a mechanistic probe for bacterial and fungal iron dependent sulfoxide synthases''
Chemistry 2020, 26, 1328 - 1334.


se

30.

Lim, D.; Gründemann, D.; Seebeck, F. P.
''Total Synthesis and functional characterisation of Selenoneine''
Angew. Chem. Int. Ed. 2019, 58, 15026 - 15030.


DM

29.

Miarzlou, D.A.; Leisinger, F.; Joss, D.; Häussinger, D.; Seebeck, F. P. 
"Structure of formylglycin-generating enzyme in complex with copper and a substrate reveals an acidic pocket for binding and activation of molecular oxygen."
Chem. Sci., 2019, 10, 7049 - 7058.


CL

28.

Liao, C & Seebeck, F. P. 
"S-adenosylhomocysteine as a methyl transfer catalyst in biocatalytic methylation reaction."
Nature Catalysis, 2019, 2, 696 - 701.


AM

27.

Maurer, A*; Leisinger, F.*; Lim, D.; Seebeck, F. P. 
"Structure and mechanism of ergothionase from Treponema denticola."
Chem. Eur. J., 2019, 25, 10298 - 10303.


JACS2019-2

26.

Leisinger, F*.; Burn R*.; Meury, M.; Lukat, P.; Seebeck, F. P. 
"Structural and mechanistic basis for anaerobic ergothioneine biosynthesis." 
J. Am. Chem. Soc., 2019, 141, 6906 - 6914.


pub25

25.

Stampfli A.R.; Goncharenko K.V.; Meury M.; Dubey B.N.; Schirmer T.; Seebeck F.P.
"An Alternative Active Site Architecture for O2 Activation in the Ergothioneine Biosynthetic EgtB from Chloracidobacterium thermophilum"
J. Am. Chem. Soc. 2019, 141, 5275 - 5285.


LC

24.

Liao C.; Seebeck F.P.
"In vitro Reconstitution of Bacterial DMSP Biosynthesis"
Angew. Chem. Int. Ed. Engl. 2019, 58, 3553 - 3556.


pub32

23.

Castellano I.; Seebeck F.P.
"On ovothiol biosynthesis and biological roles: from life in the ocean to therapeutic potential"
Nat. Prod. Rep. 2018, 35, 1241 - 1250.


22.

Gamage A.M.; Liao C.; Cheah I.K.; Chen Y.; Lim D.R.X.; Ku J.W.K.; Chee R.S.L.; Gengenbacher M.; Seebeck F.P.; Halliwell B.; Gan Y.H. 
"The Proteobacterial Species Burkholderia Pseudomallei Produces Ergothioneine, which Enhances Virulence in Mammalian Infection"
FASFEB J. 2018, 6395 - 6409.


pub30

21.

Misson L.; Burn R.; Vit A.; Hildesheim J.; Beliaeva M.A.; Blankenfeldt W.; Seebeck F.P. 
"Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD"
ACS Chem. Biol. 2018, 13, 1333 - 1342.


LC

20.

Liao C.; Seebeck F.P. 
"Convergent Evolution of Ergothioneine Biosynthesis in Cyanobacteria"
Chembiochem. 2017, 18, 2115 - 2118.


RB

19.

Burn R.; Misson L.; Meury M.; Seebeck F.P. 
"Anaerobic Origin of Ergothioneine"
Angew. Chem. Int. Ed. Engl. 2017, 56, 12508 - 12511.


MK

18.

Knop M.; Lemnaru R.; Seebeck F.P. 
"Mutation of Conserved Residues Increases in Vitro Activity of Formylglycine-Generating Enzyme"
Chembiochem. 2017, 18, 1755 - 1761.


pub26

17.

Faponle A.S.; Seebeck F.P.; de Visser S.P. 
"Sulfoxide Synthase versus Cysteine Dioxygenase Reactivity in a Nonheme Iron Enzyme"
J. Am. Chem. Soc. 2017, 139, 9259 - 9270.


MM

16.

Meury M.; Knop M.; Seebeck F.P. 
"Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycin-Generating Enzyme"
Angew. Chem. Int. Ed. Engl. 2017, 56, 8115 - 8119.


pub24

15.

Knop M.; Dang T.Q.; Jeschke G.; Seebeck F.P. 
"Copper is a Cofactor of the Formylglycine-Generating Enzyme"
Chembiochem. 2017, 18, 161 - 165.



FGE2015_abstract

13.

Knop M.; Engi P.; Lemnaru R; Seebeck F.P.
"In Vitro Reconstitution of Formylglycine-Generating Enzymes Requires Copper(I)"
Chembiochem. 2015, 2147 - 2150.


EgtC

12.

Vit A.; Mashabela, G.T.; Blankenfeldt W.; Seebeck F.P.
"Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC"
Chembiochem. 2015, 16, 1490 - 1496.


EgtB

11.

Goncharenko K.V.; Vit A.; Blankenfeldt W.; Seebeck F.P.
"Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway"
Angew Chem Int Ed Engl. 2015, 54, 2821 - 2824.


EgtD

10.

Vit A.; Misson L.; Blankenfeldt W.; Seebeck FP.
"Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis"
Chembiochem. 2015, 16, 119 - 125.


EgtD1

9.

Vit A.; Misson L.; Blankenfeldt W.; Seebeck F.P.
"Crystallization and preliminary X-ray analysis of the ergothioneine-biosynthetic methyltransferase EgtD"
Acta Crystallogr F Struct Biol Commun. 2014, 70, 676 - 680.  


OvoA

8.

Mashabela, G.T.; Seebeck, F.P.
"Substrate specificity of an oxygen dependent sulfoxide synthase in ovothiol biosynthesis"
Chem. Commun. 2013, 49, 714 - 716.


Thiohistidine_bisynth

7.

Seebeck, F.P.
"Thiohistidine biosynthesis"
CHIMIA. 2013, 67, 333 - 336.


lanti_toc

6.

Hofmann, F.T.; Szostak, J.W.; Seebeck, F.P.
"In vitro selection of functional lantipeptides"
J. Am. Chem. Soc. 2012, 134, 8038 - 8041.


abstract facial

5.

Amrein, B.; Schmid, M.; Collet, G.; Cuniasse, P.; Gilardoni, F.; Seebeck, F.P.; Ward, T.R.
"Identification of two-histidines one-carboxylate binding motifs in proteins amenable to facial coordination to metals"
Metallomics.  2012, 4, 379 - 388.


public_04

4.

Frank T. Hofmann, F.T.; Lindemann, C.; Salia, H.; Adamitzki, P.; Karanicolas, J.; Seebeck, F.P. 
"A phosphoarginine containing peptide as an artificial SH2 ligand"
Chem. Commun. 2011, 47, 10335 - 10337.


public03

3.

Seebeck, F. P.; Ricardo, A.; Szostak, J. W. 
"Artificial lantipeptides from in vitro translations"
Chem. Commun. 2011, 47, 6141 - 6143.


public02

2.

Braunshausen, A.; Seebeck, F.P. 
"Identification and characterization of the first Ovothiol biosynthetic Enzyme" 
J. Am. Chem. Soc. 2011, 133, 1757 - 1759


public01

1.

Seebeck, F.P. 
"In vitro reconstitution of mycobacterial ergothioneine biosynthesis"
J. Am. Chem. Soc. 2010, 132, 6632 - 6633.

 

* equal contribution