Xiaojin Wen

Office O03.001
xiaojin.wen@clutterunibas.ch
phone +41 (0)61 207 59 41 

University Basel
Department of chemistry

BPR 1096, Rosental Mitte, Mattenstrasse 22
4058 Basel 

Publications

Wen, X; Leopold, V. and Seebeck, F. P.
Enzymatic synthesis of S-adenosyl-L-homocysteine and its nucleoside analogs from racemic homocysteine thiolactone
Chem. Sci. 2024, in press

Gericke, L.; Mhaindarkar, D.; Karst, L. C.; Jahn, S.; Kuge, M.; Mohr, M. K. F.; Gagsteiger, J.; Cornelissen, N. V.; Wen, X.; Mordhorst, S.; Jessen, H. J.; Rentmeister, A.; Seebeck, F. P.; Layer, G.; Loenarz, C.; Andexer, J. N.
"Biomimetic S-Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes"
ChemBioChem. 2023, e202300133.

Wen, X.; Leisinger, F.; Leopold, V.; Seebeck, F. P.
"Synthetic reagents for enzyme-catalyzed methylation"
Angew. Chem. Int. Ed. 2022,  e202208746.

Lim, D.; Wen, X.; Seebeck, F. P.
''Selenoimidazolium salts as supramolecular reagents for protein alkylation''
ChemBioChem. 2020, 21, 3515-3520.

Previous work:

Wen X.; Li X.; Luo X.; Wang W.; Song S.; Jiao N.
"Intramolecular Csp3-H/C-C bond amination of alkyl azides for the selective synthesis of cyclic imines and tertiary amines"
Chem. Sci. 2020, 11, 4482 - 4487.

Liu J.; Zhang C.; Zhang Z.; Wen X.; Duo X.; Wei J.; Qiu X.; Song S.; Jiao N.
"Nitromethane as a nitrogen donor in Schmidt-type formation of amides and nitriles"
Science 2020, Vol. 367,Issue 6475, 281 - 285.

Qin Q.; Luo X.; Wei J.; Zhu Y.; Wen X.; Song S.; Jiao N.
"Acetonitrile Activation: An Effective Two-Carbon Unit for Cyclization"
Angew. Chem. Int. Ed. Engl. 2019, 58, 4376 - 4380.

Zhu Y.; Huang K.; Pan J.; Qiu X.; Luo X.; Qin Q.; Wei J.; Wen X.; Zhang L.; Jiao N.
"Silver-catalyzed remote Csp³-H functionalization of aliphatic alcohols"
Nat. Commun. 2018, 9, 2625.

Liu J.; Wen X.; Qin C.; Li X.; Luo X.; Sun A.; Zhu B.; Song S.; Jiao N.
"Oxygenation of Simple Olefins through Selective Allylic C-C Bond Cleavage: A Direct Approach to Cinnamyl Aldehydes"
Angew. Chem. Int. Ed. Engl. 2017, 56, 11940 - 11944.

Tang C.; Zou M.; Liu J.; Wen X.; Sun X.; Zhang Y.; Jiao N. 
"Rh-Catalyzed Direct Amination of Unactivated C(sp(3))-H bond with Anthranils Under Mild Conditions"
Chemistry 2016, 32, 11165 - 11169.

Zu, Y., Wen X., Song, S., Jiao, N.
''Silver-Catalyzed Radical Transformation of Aliphatic Carboxylic Acids to Oxime Ethers''
ACS Catal. 2016, 6, pp 6465–6472.