Zhong Li

Dr. Zhong Li

Office O03.001
zhong.li@clutterunibas.ch
phone +41 (0)61 207 59 41 

University Basel
Department of Chemistry
BPR 1096, Rosental Mitte, Mattenstrasse 24a
4058 Basel 


Publications

Previous work:

Li, Z.; Zhang, L.; Kang, X.; Jiang, Y.; Du, J.; Zhang, X.; Meng, L.; Wu, Q.; Du, L.; Li, X.; Hu, Y.; Xie, Z.; Jiang, X.; Tang, Y.; Wu, R.; Guo, R.; Li, S.
Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase.
Nat. Commun., 2023, 14, 4001.

Li, Z.; Zhang,J.; Li S.; Zhang, W.
Deep-sea microbe derived cytochrome P450 enzymes and natural product biosynthesis.
J. Xiaman Univ. Nat. Sci., 2022, 61, 484-495.

Li, Z.; Li, S.; Du, L.; Zhang, X.; Jiang, Y.; Liu, W.; Zhang, W.; Li, S.
Engineering bafilomycin high-producers by manipulating regulatory and biosynthetic genes in the marine bacterium Streptomyces lohii.
Mar. Drugs2021, 19, 29.

Jiang, Y.; Peng, W.; Li, Z.; You, C.; Zhao, Y.; Tang, D.; Wang, B.; Li, S.
Unexpected reactions of α,β-unsaturated fatty acids provide insight into the mechanisms of CYP152 peroxygenases.
Angew. Chem. Int. Ed., 2021, 60, 24694-24701.

Li, Z.; Jiang, Y.; Zhang, X.; Chang, Y.; Li, S.; Zhang, X.; Zheng, S.; Geng, C.; Men, P.; Ma, L.; Yang, Y.; Gao, Z.; Tang, Y.; Li, S.
Fragrant venezuelaenes A and B with a 5–5–6–7 tetracyclic skeleton: discovery, biosynthesis, and mechanisms of central catalysts.
ACS Catal., 2020, 10, 5846-5851.

Li, Z.; Jiang, Y.; Guengerich, F. P.; Ma, L.; Li, S.; Zhang, W.
Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications.
J. Biol. Chem., 2020, 295, 833-849.

Li, Z.; Du, L.; Zhang, W.; Zhang, X.; Jiang, Y.; Liu, K.; Men, P.; Xu, H.; Fortman, J. L.; Sherman, D. H.; Yu, B.; Gao, S.; Li, S.
Complete elucidation of the late steps of bafilomycin biosynthesis in Streptomyces lohii.
J. Biol. Chem., 2017, 292, 7095-7104.

Li, Z.; Zhang, W.; Li, S.
Cytochrome P450 enzymes and microbial drug development – A review.
Acta Microbiol. Sin., 2016, 56, 496-515.