55.
Wen, X; Leopold, V. and Seebeck, F. P.
Enzymatic synthesis of S-adenosyl-L-homocysteine and its nucleoside analogs from racemic homocysteine thiolactone
Chem. Sci. 2024, 15, 15900-15906
54.
Nalivaiko, E. Y.; Seebeck, F. P.
"A Rhodanese-Like Enzyme that Catalyzes Desulfination of Ergothioneine Sulfinic Acid"
ChemBioChem 2024, e202400131
53.
Vasseur, C. M.; Karunasegaram, D.; Seebeck, F. P.
"Structure and Substrate Specificity of S-Methyl Thiourocanate Hydratase."
ACS Chem. Biol. 2024,19, 3, 718–724
52.
Nalivaiko, E. Y.*; Vasseur C. M.*; Seebeck, F. P.
"Enzyme-Catalyzed Oxidative Degradation of Ergothioneine."
Angew. Chem. Int. Ed. 2024, e202318445.
51.
Peng, J.; Hughes, G. R.; Müller, M. M.; Seebeck, F. P.
"Enzymatic Fluoromethylation as a Tool for ATP-independent Ligation"
Angew. Chem. Int. Ed. 2023, e202312104.
50.
Reed, J. H.; Seebeck, F. P.
"Reagent Engineering for Biocatalysis"
Angew. Chem. Int. Ed. 2023, e202311159.
49.
Gericke, L.; Mhaindarkar, D.; Karst, L. C.; Jahn, S.; Kuge, M.; Mohr, M. K. F.; Gagsteiger, J.; Cornelissen, N. V.; Wen, X.; Mordhorst, S.; Jessen, H. J.; Rentmeister, A.; Seebeck, F. P.; Layer, G.; Loenarz, C.; Andexer, J. N.
"Biomimetic S-Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes"
ChemBioChem. 2023, e202300133.
48.
Hartmann, L.; Seebeck, F. P.; Schmalz, H. G.; Gründemann, D.
"Isotope-labeled ergothioneine clarifies the mechanism of reaction with singlet oxygen"
Free Radic. Biol. Med. 2023, 198, 12-26.
47.
Wen, X.; Leisinger, F.; Leopold, V.; Seebeck, F. P.
"Synthetic reagents for enzyme-catalyzed methylation"
Angew. Chem. Int. Ed. 2022, e202208746.
46.
Beliaeva, M. A.; Seebeck, F. P.
"Discovery and characterization of the metallopterin-dependent ergothioneine synthase from Caldithrix abyssi"
JACS Au, 2022, 2, 2098-2107.
45.
Beliaeva, M. A.; Atac, R.; Seebeck, F. P.
Bacterial Degradation of Nτ-Methylhistidine.
ACS Chem. Biol., 2022, 17, 7, 1989-1995.
44.
Peng, J.*; Liao, C.*; Bauer, C.; Seebeck, F. P.
''Fluorinated S-adenosylmethionine as a reagent for enzyme-catalyzed flouromethylation''
Angew. Chem. Int. Ed. 2021, 60, 27178 - 27183.
43.
Duncombe T.A.; Ponti A.; Seebeck, F. P.; Dittrich P.S.
"UV-Vis Spectra-Activated Droplet Sorting for Label-Free Chemical Identification and Collection of Droplets."
Anal. Chem., 2021, 93, 38, 13008 - 13013.
42.
Schneider P.; Henssen B.; Paschold B.; Chapple B.P.; Schatton M.; Seebeck, F. P.; Classen T.; Pietruszka J.
"Biocatalytic C3-Indole Methylation – A Useful Tool for the Natural Product Inspired Stereoselective Synthesis of Pyrroloindoles."
Angew. Chem. Int. Ed., 2021, 60, 23412 - 23418.
41.
Beliaeva M. A.; Leisinger F.; Seebeck, F. P.
"In Vitro Reconstitution of a Five-Step Pathway for Bacterial Ergothioneine Catabolism."
ACS Chem. Biol., 2021, 16, 397 - 403.
40.
Leisinger F.; Miarzlou, D.A.; Seebeck, F. P.
"Non-coordinative binding of O2 at the active site center of a copper-dependent enzyme."
Angew. Chem. Int. Ed., 2021, 133, 6219 - 6224.
39.
Beliaeva M. A.; Burn R.; Lim D.; Seebeck, F. P.
''In vitro production of ergothioneine isotopologues''
Angew. Chem. Int. Ed. 2020, 60, 5209 - 5212.
38.
Lim D.; Wen X.; Seebeck, F. P.
''Selenoimidazolium salts as supramolecular reagents for protein alkylation''
ChemBioChem. 2020, 21, 3515 - 3520.
37.
Stampfli A. R.; Seebeck, F. P.
''The catalytic mechanism of sulfoxide synthases''
Current Opinion in Chemical Biology 2020, 59, 111 - 118.
36.
Flückiger S.; Igareta N. V.; Seebeck, F. P.
''Convergent evolution of fungal cysteine dioxygenases''
ChemBioChem. 2020, 21, 3082 - 3086.
35.
Maurer A.; Seebeck, F. P.
''Reexamination of the ergothioneine biosynthetic methyltransferase EgtD from Mycobacterium tuberculosis as a protein kinase substrate''
ChemBioChem. 2020, 21, 2908 - 2911.
34.
Stampfli A. R.; Blankenfeldt, W; Seebeck, F. P.
''Structural basis of ergothioneine biosynthesis''
Current Opinion in Structural Biology 2020, 65, 1 - 8.
33.
Liao C.; Seebeck, F. P.
''Asymmetric β-methylation of L- and D-α-amino acids by a self-contained enzyme cascade''
Angew. Chem. Int. Ed. 2020, 59, 7184 - 7187.
32.
Milito, A.; Castellano, I.; Burn, R.; Seebeck, F. P.; Burnet, C.; Palumbo, A.
''First evidence of ovothiol biosynthesis in marine diatoms''
Free Radic Biol Med. 2020, 152, 680 - 688.
31.
Goncharenko, K.V.; Flückiger S.; Liao C.; Lim, D.; Stampfli A.R.; Seebeck, F. P.
''Selenocysteine as a substrate, an inhibitor and a mechanistic probe for bacterial and fungal iron dependent sulfoxide synthases''
Chemistry 2020, 26, 1328 - 1334.
30.
Lim, D.; Gründemann, D.; Seebeck, F. P.
''Total Synthesis and functional characterisation of Selenoneine''
Angew. Chem. Int. Ed. 2019, 58, 15026 - 15030.
29.
Miarzlou, D.A.; Leisinger, F.; Joss, D.; Häussinger, D.; Seebeck, F. P.
"Structure of formylglycin-generating enzyme in complex with copper and a substrate reveals an acidic pocket for binding and activation of molecular oxygen."
Chem. Sci., 2019, 10, 7049 - 7058.
28.
Liao, C & Seebeck, F. P.
"S-adenosylhomocysteine as a methyl transfer catalyst in biocatalytic methylation reaction."
Nature Catalysis, 2019, 2, 696 - 701.
27.
Maurer, A.*; Leisinger, F.*; Lim, D.; Seebeck, F. P.
"Structure and mechanism of ergothionase from Treponema denticola."
Chem. Eur. J., 2019, 25, 10298 - 10303.
26.
Leisinger, F.*; Burn R.*; Meury, M.; Lukat, P.; Seebeck, F. P.
"Structural and mechanistic basis for anaerobic ergothioneine biosynthesis."
J. Am. Chem. Soc., 2019, 141, 6906 - 6914.
25.
Stampfli A.R.; Goncharenko K.V.; Meury M.; Dubey B.N.; Schirmer T.; Seebeck F.P.
"An Alternative Active Site Architecture for O2 Activation in the Ergothioneine Biosynthetic EgtB from Chloracidobacterium thermophilum"
J. Am. Chem. Soc. 2019, 141, 5275 - 5285.
24.
Liao C.; Seebeck F.P.
"In vitro Reconstitution of Bacterial DMSP Biosynthesis"
Angew. Chem. Int. Ed. Engl. 2019, 58, 3553 - 3556.
23.
Castellano I.; Seebeck F.P.
"On ovothiol biosynthesis and biological roles: from life in the ocean to therapeutic potential"
Nat. Prod. Rep. 2018, 35, 1241 - 1250.
22.
Gamage A.M.; Liao C.; Cheah I.K.; Chen Y.; Lim D.R.X.; Ku J.W.K.; Chee R.S.L.; Gengenbacher M.; Seebeck F.P.; Halliwell B.; Gan Y.H.
"The Proteobacterial Species Burkholderia Pseudomallei Produces Ergothioneine, which Enhances Virulence in Mammalian Infection"
FASFEB J. 2018, 6395 - 6409.
21.
Misson L.; Burn R.; Vit A.; Hildesheim J.; Beliaeva M.A.; Blankenfeldt W.; Seebeck F.P.
"Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD"
ACS Chem. Biol. 2018, 13, 1333 - 1342.
20.
Liao C.; Seebeck F.P.
"Convergent Evolution of Ergothioneine Biosynthesis in Cyanobacteria"
Chembiochem. 2017, 18, 2115 - 2118.
19.
Burn R.; Misson L.; Meury M.; Seebeck F.P.
"Anaerobic Origin of Ergothioneine"
Angew. Chem. Int. Ed. Engl. 2017, 56, 12508 - 12511.
18.
Knop M.; Lemnaru R.; Seebeck F.P.
"Mutation of Conserved Residues Increases in Vitro Activity of Formylglycine-Generating Enzyme"
Chembiochem. 2017, 18, 1755 - 1761.
17.
Faponle A.S.; Seebeck F.P.; de Visser S.P.
"Sulfoxide Synthase versus Cysteine Dioxygenase Reactivity in a Nonheme Iron Enzyme"
J. Am. Chem. Soc. 2017, 139, 9259 - 9270.
16.
Meury M.; Knop M.; Seebeck F.P.
"Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycin-Generating Enzyme"
Angew. Chem. Int. Ed. Engl. 2017, 56, 8115 - 8119.
15.
Knop M.; Dang T.Q.; Jeschke G.; Seebeck F.P.
"Copper is a Cofactor of the Formylglycine-Generating Enzyme"
Chembiochem. 2017, 18, 161 - 165.
14.
Goncharenko K.V.; Seebeck F.P.
"Conversion of non-heme iron-dependent sulfoxide synthase into a thiol dioxygenase by a single point mutation"
Chem. Commun. 2016, 52, 1945 - 1948.
13.
Knop M.; Engi P.; Lemnaru R; Seebeck F.P.
"In Vitro Reconstitution of Formylglycine-Generating Enzymes Requires Copper(I)"
Chembiochem. 2015, 2147 - 2150.
12.
Vit A.; Mashabela, G.T.; Blankenfeldt W.; Seebeck F.P.
"Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC"
Chembiochem. 2015, 16, 1490 - 1496.
11.
Goncharenko K.V.; Vit A.; Blankenfeldt W.; Seebeck F.P.
"Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway"
Angew Chem Int Ed Engl. 2015, 54, 2821 - 2824.
10.
Vit A.; Misson L.; Blankenfeldt W.; Seebeck FP.
"Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis"
Chembiochem. 2015, 16, 119 - 125.
9.
Vit A.; Misson L.; Blankenfeldt W.; Seebeck F.P.
"Crystallization and preliminary X-ray analysis of the ergothioneine-biosynthetic methyltransferase EgtD"
Acta Crystallogr F Struct Biol Commun. 2014, 70, 676 - 680.
8.
Mashabela, G.T.; Seebeck, F.P.
"Substrate specificity of an oxygen dependent sulfoxide synthase in ovothiol biosynthesis"
Chem. Commun. 2013, 49, 714 - 716.
7.
Seebeck, F.P.
"Thiohistidine biosynthesis"
CHIMIA. 2013, 67, 333 - 336.
6.
Hofmann, F.T.; Szostak, J.W.; Seebeck, F.P.
"In vitro selection of functional lantipeptides"
J. Am. Chem. Soc. 2012, 134, 8038 - 8041.
5.
Amrein, B.; Schmid, M.; Collet, G.; Cuniasse, P.; Gilardoni, F.; Seebeck, F.P.; Ward, T.R.
"Identification of two-histidines one-carboxylate binding motifs in proteins amenable to facial coordination to metals"
Metallomics. 2012, 4, 379 - 388.
4.
Frank T. Hofmann, F.T.; Lindemann, C.; Salia, H.; Adamitzki, P.; Karanicolas, J.; Seebeck, F.P.
"A phosphoarginine containing peptide as an artificial SH2 ligand"
Chem. Commun. 2011, 47, 10335 - 10337.
3.
Seebeck, F. P.; Ricardo, A.; Szostak, J. W.
"Artificial lantipeptides from in vitro translations"
Chem. Commun. 2011, 47, 6141 - 6143.
2.
Braunshausen, A.; Seebeck, F.P.
"Identification and characterization of the first Ovothiol biosynthetic Enzyme"
J. Am. Chem. Soc. 2011, 133, 1757 - 1759
1.
Seebeck, F.P.
"In vitro reconstitution of mycobacterial ergothioneine biosynthesis"
J. Am. Chem. Soc. 2010, 132, 6632 - 6633.
* equal contribution